PANS & PANDAS Treatment

The Comprehensive Diagnostic Deep Dive

The In-Depth Clinical Evaluation

• What It Is: A detailed, one-on-one consultation with a HyperCharge Health provider to map your child's full symptom timeline and health history, establishing a crucial therapeutic partnership with your family.

The Extensive Laboratory Panel

• What It Is: A comprehensive battery of blood tests designed to identify infectious triggers, assess immune function, and rule out other conditions. While PANS/PANDAS is a clinical diagnosis, this workup is essential for guiding a personalized treatment protocol.

• How It Works (The Science): Based on national consensus guidelines, our iterative panel starts with core tests and expands based on history and severity.

• Infectious Triggers Panel

  • Includes a strep throat culture, ASO and Anti-DNase B titers (for PANDAS), and serologies for other common triggers like Mycoplasma pneumoniae, Epstein-Barr Virus (EBV), and Herpes Simplex Virus (HSV). In a Lyme-endemic area like Minnesota, testing for tick-borne illnesses is also considered.

• Immune Function & Autoimmune Panel

  • We assess quantitative immunoglobulins (IgG, IgA, IgM) with subclasses to check for underlying immunodeficiencies. We also screen for autoimmune markers like Antinuclear Antibodies (ANA) and anti-thyroid antibodies to understand the degree of immune dysregulation.

• Inflammation & General Health Panel

  • We measure markers of systemic inflammation like C-reactive protein (CRP) and ESR, along with a complete blood count (CBC) and comprehensive metabolic panel (CMP) to get a full picture of your child's overall health.

Advanced Brain Mapping: Quantitative EEG (qEEG)

• What It Is: A non-invasive tool that provides a functional map of your child's brain activity.

• Our Unique Approach: While not yet a national standard for diagnosis, we utilize qEEG as an advanced, personalized assessment tool. Standard lab tests show us what's happening in the blood; the qEEG shows us the downstream effect on the brain.

• How It Works (The Science): The qEEG analyzes your child's brainwave patterns, identifying abnormalities in frequency, amplitude, and connectivity. For PANS/PANDAS, it can reveal patterns of dysregulation that correlate with OCD, anxiety, and tics. This functional data is invaluable, as it allows us to personalize and track the effectiveness of our neuro-therapies, like TMS, with objective data.

The Gut-Brain-Immune Axis Restoration Program

Healing the Gut to Heal the Brain

• What It Is: A dedicated program to heal the gut lining, eradicate pathogenic bacteria or yeast, and restore a healthy microbiome.

• Why It's Critical for PANS/PANDAS: A compromised gut barrier ("leaky gut") allows bacterial fragments to enter the bloodstream, triggering a massive inflammatory response that directly fuels the neuroinflammation in the brain. Healing the gut is therefore essential to calming the entire system.

• How It Works (The "4R" Protocol): We use advanced stool testing to guide a protocol of Remove (pathogens), Replace (enzymes), Reinoculate (probiotics), and Repair (using nutrients and healing peptides like BPC-157).

The Five Pillars of Biohacking: A Gentle, Systemic Approach

Foundational Support for a Sensitive System

• What They Are: Our suite of non-invasive technologies is uniquely suited for the sensitivities of PANS/PANDAS patients.

• How They Help PANS/PANDAS:

  • Photobiomodulation (PBM): This is a cornerstone therapy. It powerfully reduces both systemic inflammation and neuroinflammation and supports mitochondrial function to provide stressed brain cells with energy.

  • Pulsed Electromagnetic Field (PEMF) Therapy: Reduces systemic inflammation and improves microcirculation to deliver oxygen to the brain.

  • NanoVi Therapy: Helps cells repair the massive protein damage caused by the oxidative stress of neuroinflammation.

  • Advanced Oxygen Therapy (EWOT): Gently increases oxygenation to reduce the inflammatory state in tissues.

  • Acupuncture: Can be a powerful tool for older children to modulate the immune system and calm the "fight or flight" response.

Advanced Neuro-Restoration

Transcranial Therapies

• What They Are: A suite of non-invasive technologies designed to directly and safely treat the brain.

• Our Neuro-Restoration Toolkit:

  • Transcranial Photobiomodulation (tPBM): By applying near-infrared light to the scalp, we can penetrate the skull to improve mitochondrial function and reduce inflammation directly within brain cells.

  • Exomind Transcranial Magnetic Stimulation (TMS): For adolescents and young adults, this FDA-cleared therapy uses magnetic pulses to gently and non-invasively retrain the neural circuits hijacked by the inflammatory process, directly addressing severe OCD, anxiety, and depressive symptoms.

The Neuro20 Suit: Re-establishing the Mind-Body Connection

• What It Is: A revolutionary suit that uses electrical muscle stimulation (EMS) during a safe, low-impact, and often fun session.

• How It Helps PANS/PANDAS: The condition often disrupts motor control, leading to tics and poor coordination. The Neuro20 suit helps rebuild this critical connection. It helps re-establish neural pathways to improve motor control and boosts Brain-Derived Neurotrophic Factor (BDNF), a key molecule for neuroplasticity and the growth of new, healthy neurons.

Advanced Peptide Stacks

• What It Is: The use of specific, small signaling molecules (peptides) to provide targeted support.

• How It Helps PANS/PANDAS: We create personalized peptide stacks designed for gentle modulation. Immune-Modulating Peptides are used to rebalance a confused immune system. Anti-inflammatory and neuro-supportive peptides like KPV and Selank can offer pure anti-inflammatory signals and reduce anxiety.

Advanced Immunomodulation: A Collaborative Approach

Intravenous Immunoglobulin (IVIg) Therapy

• What It Is: The intravenous infusion of healthy antibodies, considered a first-line immunomodulatory treatment for moderate to severe PANS/PANDAS by leading academic centers.

• Our Collaborative Role: While HyperCharge Health does not directly administer IVIg, we recognize its critical importance. For children who meet the criteria for this therapy, we work in close partnership with major medical centers in the Twin Cities and beyond. We will facilitate the referral and co-manage your child's care, ensuring they receive this vital treatment while continuing all of our foundational and advanced supportive therapies at our clinic to maximize the benefits and support a lasting recovery.

As part of our commitment to becoming the most comprehensive destination for PANS/PANDAS care in the country, we are actively developing our Concierge Neuro-Immune Recovery Intensive. This program will be designed for families traveling to our Edina clinic for an immersive, multi-week healing experience. Future additions to this program will include:

• Therapeutic Plasma Exchange (TPE / Plasmapheresis): The most powerful intervention for rapidly removing the harmful autoantibodies that attack the brain in severe, acute cases.

• A fully integrated, residential-style support program for families undergoing the intensive treatment block.