Patient Education Articles

The Biophysical Imperative in Chronic Lyme Disease: A Comprehensive Review of Functional Medicine Limitations and the Case for Regenerative Biohacking & Neuromodulation
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The Biophysical Imperative in Chronic Lyme Disease: A Comprehensive Review of Functional Medicine Limitations and the Case for Regenerative Biohacking & Neuromodulation

Post-Treatment Lyme Disease Syndrome (PTLDS) and Chronic Lyme Disease (CLD) represent a complex multisystemic failure characterized by persistent infection, immune dysregulation, mitochondrial exhaustion, and profound neuropsychiatric sequelae. The current integrative standard of care—Functional Medicine—utilizes systems biology and targeted nutraceuticals to modulate these pathways. While biochemically sound and diagnostically superior to conventional models, this approach frequently encounters clinical ceilings in chronic cases. These limitations stem from compromised gastrointestinal absorption, severe metabolic exhaustion (the "metabolic tax" of digestion), and the physical impermeability of bacterial biofilms.

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